RNA Details
Disease Name
endomyocardial fibrosis
Tissue
heart
RNA Symbol
mir-29c
RNA ID
RNA Type
miRNA
Alteration Pattern
down regulation
Species
mus musculus
Detection Methods
PCR; Masson's trichrome staining etc.
Target
COL 1A1;COL1A2;COL3A1;COL5A1;FBN1
Pathway
TGF-BETA SIGNALING PATHWAY
PubMed ID
Title
MiR-29c is implicated in the cardioprotective activity of Panax notoginseng saponins against isoproterenol-induced myocardial fibrogenesis
Year
2017
Function
"Panax notoginseng saponins(PNS) could in part implicate increased expression of miR-29c in the heart, which may help increase the understanding of the pharmacological activities of PNS in treating cardiovascular disorders."